Hands off the Ayatollah.

WASHINGTON (AP) — President Barack Obama heralded a historic nuclear agreement with Iran Tuesday as an opportunity for the longtime foes to move in a “new direction,” while sharply warning Congress that it would be irresponsible to block the accord.

“No deal means a greater chance of more war in the Middle East,” Obama said in early morning remarks from the White House.

Obama, accompanied by Vice President Joe Biden, spoke shortly after negotiators in Vienna announced the landmark deal aimed at curbing Iran’s nuclear program for more than a decade in exchange for billions of dollars in international sanctions relief. The president said the agreement, hammered out through nearly two years of negotiations, would cut off all of Iran’s pathways to a bomb and give the international community unprecedented access to the country’s nuclear facilities.